Ying-Yong Zhao Selected Research

Adenine

2/2021	The Dysregulation of Eicosanoids and Bile Acids Correlates with Impaired Kidney Function and Renal Fibrosis in Chronic Renal Failure.
1/2021	Shenkang Injection and Its Three Anthraquinones Ameliorates Renal Fibrosis by Simultaneous Targeting IƙB/NF-ƙB and Keap1/Nrf2 Signaling Pathways.
1/2020	Poricoic acid A as a modulator of TPH-1 expression inhibits renal fibrosis via modulating protein stability of β-catenin and β-catenin-mediated transcription.
1/2018	Rhubarb Protect Against Tubulointerstitial Fibrosis by Inhibiting TGF-β/Smad Pathway and Improving Abnormal Metabolome in Chronic Kidney Disease.
1/2018	An Integrated Lipidomics and Phenotype Study Reveals Protective Effect and Biochemical Mechanism of Traditionally Used Alisma orientale Juzepzuk in Chronic Kidney Disease.
7/2017	The link between phenotype and fatty acid metabolism in advanced chronic kidney disease.
12/2016	Metabolomics insights into activated redox signaling and lipid metabolism dysfunction in chronic kidney disease progression.
2/2016	An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure.
7/2013	Urinary metabonomic study of the surface layer of Poria cocos as an effective treatment for chronic renal injury in rats.
2/2013	Intrarenal metabolomic investigation of chronic kidney disease and its TGF-β1 mechanism in induced-adenine rats using UPLC Q-TOF/HSMS/MS(E).

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Ying-Yong Zhao Research Topics

Disease

40	Fibrosis (Cirrhosis) 11/2022 - 12/2011
20	Chronic Renal Insufficiency 03/2021 - 10/2012
17	Neoplasms (Cancer) 02/2021 - 07/2010
15	Inflammation (Inflammations) 01/2022 - 12/2014
14	Chronic Kidney Failure (Chronic Renal Failure) 01/2022 - 12/2011
12	Kidney Diseases (Kidney Disease) 03/2021 - 08/2013
5	Diabetic Nephropathies (Diabetic Nephropathy) 01/2022 - 06/2013
5	Ureteral Obstruction 12/2020 - 01/2018
5	Hyperlipidemias (Hyperlipidemia) 04/2017 - 01/2014
3	Hypertension (High Blood Pressure) 03/2022 - 01/2019
3	Dyslipidemias (Dyslipidemia) 02/2021 - 01/2014
3	Cardiovascular Diseases (Cardiovascular Disease) 02/2021 - 01/2014
3	Proteinuria 01/2020 - 12/2011
3	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 01/2014
3	Anemia 01/2017 - 12/2011
3	Edema (Dropsy) 12/2014 - 04/2013
2	Acute Kidney Injury (Acute Renal Failure) 03/2021 - 01/2019
2	Disease Progression 02/2021 - 01/2019
2	Renal Cell Carcinoma (Grawitz Tumor) 11/2020 - 01/2019
2	Hepatocellular Carcinoma (Hepatoma) 11/2020 - 04/2011
2	Dysbiosis 01/2020 - 12/2019
2	IGA Glomerulonephritis (IGA Nephropathy) 01/2019 - 06/2013
2	Hypoxia (Hypoxemia) 01/2019 - 01/2019
2	Chronic Tubulointerstitial Nephropathy 01/2018 - 02/2016
2	Uremia 12/2017 - 01/2016
2	Breast Neoplasms (Breast Cancer) 10/2017 - 09/2017
2	Body Weight (Weight, Body) 07/2017 - 12/2011
2	Obesity 09/2016 - 01/2014
2	Metabolic Diseases (Metabolic Disease) 10/2015 - 10/2014
1	Nephrotic Syndrome (Syndrome, Nephrotic) 01/2022
1	Membranous Glomerulonephritis (Membranous Nephropathy) 01/2022
1	Hyperglycemia 01/2021
1	Adenocarcinoma 11/2020
1	Pheochromocytoma 11/2020
1	Colonic Neoplasms (Colon Cancer) 11/2020
1	Mesothelioma 11/2020
1	Squamous Cell Carcinoma of Head and Neck 11/2020
1	Carcinosarcoma 11/2020

Drug/Important Bio-Agent (IBA)

15	Adenine FDA LinkGeneric 02/2021 - 02/2012
15	Biomarkers (Surrogate Marker)IBA 11/2020 - 01/2014
10	Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA 11/2022 - 01/2019
10	CateninsIBA 01/2021 - 01/2017
8	LipidsIBA 02/2021 - 01/2014
8	ergosta-4,6,8(14),22-tetraen-3-oneIBA 01/2021 - 10/2010
7	CreatinineIBA 03/2021 - 12/2011
7	Therapeutic UsesIBA 01/2021 - 10/2012
7	Proteins (Proteins, Gene)FDA Link 01/2021 - 05/2014
6	LigandsIBA 01/2022 - 01/2019
5	Urea (Carbamide)FDA LinkGeneric 03/2021 - 12/2011
5	AcidsIBA 12/2020 - 12/2017
5	TriterpenesIBA 12/2020 - 04/2013
5	poricoic acid AIBA 07/2020 - 01/2019
4	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2022 - 01/2018
4	NF-kappa B (NF-kB)IBA 12/2020 - 12/2016
4	RNA (Ribonucleic Acid)IBA 01/2020 - 09/2017
4	Pharmaceutical PreparationsIBA 01/2020 - 10/2012
4	Fatty Acids (Saturated Fatty Acids)IBA 07/2017 - 02/2013
4	Biological ProductsIBA 09/2016 - 04/2013
4	DiureticsIBA 12/2014 - 04/2013
3	Tryptophan (L-Tryptophan)FDA Link 01/2022 - 01/2019
3	Uremic ToxinsIBA 02/2021 - 01/2016
3	DNA (Deoxyribonucleic Acid)IBA 01/2019 - 09/2017
3	Complex MixturesIBA 11/2018 - 08/2013
3	aristolochic acid I (aristolochic acid)IBA 12/2016 - 12/2011
2	Long Noncoding RNAIBA 03/2021 - 01/2019
2	Lipoproteins (Lipoprotein)IBA 02/2021 - 01/2017
2	Bile Acids and Salts (Bile Acids)IBA 02/2021 - 02/2016
2	EicosanoidsIBA 02/2021 - 02/2015
2	ElectrolytesIBA 02/2021 - 12/2017
2	Advanced Glycation End ProductsIBA 01/2021 - 01/2019
2	FlavonoidsIBA 01/2020 - 01/2019
2	MelatoninIBA 01/2019 - 01/2019
2	MicroRNAs (MicroRNA)IBA 01/2019 - 01/2018
2	trimethyloxamine (trimethylamine N-oxide)IBA 01/2019 - 01/2016
2	ethyl acetateIBA 02/2018 - 02/2016
2	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2017 - 12/2016
2	Polysaccharides (Glycans)IBA 01/2017 - 04/2013
2	Glycerophospholipids (Phosphoglycerides)IBA 02/2016 - 02/2015
2	IndicanIBA 01/2016 - 02/2013
2	PhytochemicalsIBA 09/2015 - 08/2013
2	AntioxidantsIBA 09/2015 - 04/2013
2	Triglycerides (Triacylglycerol)IBA 08/2015 - 01/2014
1	1-methoxypyreneIBA 11/2022
1	dodecanedioic acidIBA 03/2022
1	Phosphocreatine (Neoton)IBA 03/2022
1	Phosphates (Orthophosphate)IBA 03/2022
1	1-hydroxypyreneIBA 01/2022
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2021
1	Angiopoietin-Like Protein 2IBA 01/2021
1	Angiotensin-Converting Enzyme 2IBA 01/2021
1	shenkangIBA 01/2021
1	Cannabinoid Receptors (Cannabinoid Receptor)IBA 01/2021
1	AnthraquinonesIBA 01/2021

Therapy/Procedure

13	Therapeutics 01/2022 - 06/2013
2	Drug Therapy (Chemotherapy) 01/2022 - 01/2021
2	Kidney Transplantation 01/2022 - 03/2021
2	Nephrectomy 07/2020 - 01/2018
2	Renal Dialysis (Hemodialysis) 01/2019 - 12/2017
2	Chinese Traditional Medicine (Traditional Chinese Medicine) 09/2016 - 04/2013
1	Glycemic Control 01/2021